Publicações
  1. E.F. Pinto, R.S. Santos, M.A. Antunes, L.A. Maia, G.A. Padilha, J.A. Machado, A.C.F. Carvalho, M.V.S. Fernandes, V.L. Capelozzi, M.G. de Abreu, P. Pelosi, P.R.M. Rocco, P.L. Silva. Static and dynamic transpulmonary driving pressures affect lung and diaphragm injury during pressure-controlled versus pressure-support ventilation in experimental mild lung injury in rats. Anesthesiology. 132(2):307-320, 2020. / Pubmed
     
  2. L.B. Heil, P.L. Silva, F.F. Cruz, P. Pelosi, P.R.M. Rocco. Immunomodulatory effects of anesthetic agents in perioperative medicine. Minerva Anestesiol. 86(2):181-195, 2020. / Pubmed
     
  3. L.L. Castro, J.Z. Kitoko, D.G. Xisto, P.C. Olsen, H.L.M. Guedes, M.M. Morales, M. Lopes-Pacheco, F.F. Cruz, P.R.M. Rocco. Multiple doses of adipose tissue-derived mesenchymal stromal cells induce immunosuppression in experimental asthma. Stem Cells Trans Med. 9(2):250-260, 2020. / Pubmed
     
  4. M. Lopes-Pacheco, C. Robba, P.R.M. Rocco, P. Pelosi. Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome. Cell Biol Toxicol. 36(1):83-102, 2020. / Pubmed
     
  5. F.F. Cruz, P.R.M. Rocco. The potential of mesenchymal stem cell therapy for chronic lung disease. Expert Rev Respir Med. 14(1):31-39, 2020. / Pubmed
     
  6. J.J. Marini, P.R.M. Rocco. Which component of mechanical power is most important in causing VILI? Critical Care. 24(1):39. 24:39, 2020. / Pubmed
     
  7. J. Wittenstein, M. Scharffenberg, A. Braune, R. Huhle, T. Bluth, M. Herzog, A. Güldner, L. Ball, F. Simonassi, I. Zeidler-Rentzsch, M.F. Vidal Melo, T. Koch, P.R.M. Rocco, P. Pelosi, J. Kotzerke, M.G. de Abreu, T. Kiss. Effects of variable versus nonvariable controlled mechanical ventilation on pulmonary inflammation in experimental acute respiratory distress syndrome in pigs. British Journal Of Anaesthesia. pii: S0007-0912(20)30005-2, 2020. / Pubmed
     
  8. A.L. Silva, L.H.A. Silva, F.F. Cruz, P.R.M. Rocco, M.M. Morales. Application of novel nanotechnologies in asthma. Annals of Translational Medicine. 8(5):159, 2020. / Pubmed
     
  9. F. Bloise, A. Santos, J. Brito, C. Andrade, T. Oliveira, A. Souza, K. Fontes, J.D. Silva, N.G. Blanco, P.L. Silva, P.R.M. Rocco, E. Fliers, A. Boelen, W. da Silva, T. Ortiga-Carvalho. Sepsis impairs thyroid hormone signaling and mitochondrial function in the mouse diaphragm. Thyroid. 30(7):1079-1090, 2020. / Pubmed
     
  10. L. Ball, P.L. Silva, P.R.M. Rocco, P. Pelosi. A critical approach to personalised medicine in acute respiratory distress syndrome. The Lancet Respiratory Medicine 8(3):218-219. 2020. / Pubmed
     
  11. D. Battaglini, G. Bonatti, C. Robba, P.R.M. Rocco, P. Pelosi. Mechanical Ventilation and neurocritical patients: is there a role ofr anti-neuroinflammatory therapies? Letter. Authors´ response to Giordano et al Crit Care 24:22, 2020.
     
  12. P.L. Silva, P. Pelosi, P.R.M. Rocco. Personalized pharmacological therapy for ARDS: a light at the end of the tunnel. Expert Opinion on Investigational Drugs. 29(1):49-61, 2020. / Pubmed
     
  13. A. Carla, B. Pereira, H. Boukail, J. Audard, N. Pinol-Domenech, M. de Carvalho, R. Blondonnet, R. Zhai, D. Morand, C. Lambert, V. Sapin, L.B. Ware, C.S. Calfee, J.A. Bastarache, J.G. Laffey, N.P. Juffermans, L.D. Bos, A. Artigas, P.R.M. Rocco, M.A. Matthay, D.F. McAuley, J.M. Constantin, M. Jabaudon. Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis. Respiratory Research. 21(1):81. 2020. / Pubmed
     
  14. P.L. Silva, P. Pelosi, P.R.M. Rocco. Understanding the Mysteries of Mechanical Power. Anesthesiology. 132(5):949-950, 2020. / Pubmed
     
  15. A.Y.O. Silva, E.A. Amorim, M.C. Barbosa-Silva, M.N. Lima, H.A. Oliveira, M.G. Granja, K.S. Oliveira, P.M. Fagundes, R.L.S. Neris, R.M.P. Campos, C.A. Moraes, A.L. Vallochi, P.R.M. Rocco, F.A. Bozza, H.C. Castro-Faria-Neto, T. Maron-Gutierrez. Mesenchymal stromal cells protect the blood-brain barrier, reduce astrogliosis, and prevent cognitive and behavioral alterations in surviving septic mice. Critical Care Medicine. 48(4):e290-e298, 2020. / Pubmed
     
  16. J.J. Marini, P.R.M. Rocco, L. Gattinoni. Static and dynamic contributors to VILI in clinical practice: pressure, energy, and power. Am J Respir Crit Care Med. 201(7):767-774, 2020. / Pubmed
     
  17. J.J. Marini, L. Gattinoni, P.R.M. Rocco. Estimating the damaging power of high stress ventilation. Respiratory Care. 65(7):1046-1052, 2020. / Pubmed
     
  18. A.L. da Silva, G.P. Oliveira, N. Kim, F.F. Cruz, J.Z. Kitoko, N.G. Blanco, S.V. Martini, J. Hanes, P.R.M. Rocco, J.S. Suk, M.M. Morales. Nanoparticle-based thymulin gene therapy therapeutically reverses key pathology of experimental allergic asthma. Science Advances. 6(24):eaay7973, 2020. / Pubmed
     
  19. D. Battaglini, C. Robba, A.L. Silva, C.S. Samary, P.L. Silva, F. dal Pizzol, P. Pelosi, P.R.M. Rocco. Brain–heart interaction after acute ischemic stroke. Critical Care. 24(1):163, 2020. / Pubmed
     
  20. M. Khoury, J. Cuenca, F.F. Cruz, F.E. Figueroa, P.R.M. Rocco, D.J. Weiss. Current Status of Cell-Based Therapies for Respiratory Virus Infections: Applicability to COVID-19. European Respiratory Journal. 55(6):2000858, 2020. / Pubmed
     
  21. M. Khoury, P.R.M. Rocco, D.G. Phinney, M. Krampera, I. Martin, S. Viswanathan, J.A. Nolta, K. LeBlanc, J. Galipeau, D.J. Weiss. Cell-Based Therapies for COVID-19: Proper Clinical Investigations are Essential. Cytotherapy. S1465-3249(20)30616-2, 2020. / Pubmed
     
  22. F.S. Aguiar, A.S. Melo, A.M.S. Araújo, A.P. Cardoso, S.A.L. Souza, M. Lopes-Pacheco, F.F. Cruz, D.G. Xisto, K.D. Asensi, L. Faccioli, A.B.S. Salgado, M.C.P.P. Landesmann, R.C.S. Goldenberg, B. Gutfilen, M.M. Morales, P.R.M. Rocco, J.R.L. Silva. Autologous bone marrow-derived mononuclear cell therapy in three patients with severe asthma. Stem Cell Res Ther. 1;11(1): 167, 2020. / Pubmed
     
  23. C. Robba, D. Battaglini, L. Ball, N. Patroniti, M. Loconte, I. Brunetti, A. Vena, D.R. Giacobbe, M. Bassetti, P.R.M. Rocco, P. Pelosi. Distinct phenotypes require distinct respiratory management strategies in severe COVID-19. Respiratory Physiology & Neurobiology, v. 279, 103455. 2020. / Pubmed
     
  24. D. Battaglini, C. Robba, L. Ball, F.F. Cruz, P.L. Silva, P. Pelosi, P.R.M. Rocco. Emerging therapies for COVID-19 pneumonia. Expert Opinion on Investigational Drugs. 1:1-5. 2020. / Pubmed
     
  25. M. Cancio, R. Ciccocioppo, P.R.M. Rocco, B. Levine, V. Bronte, C.M. Bollard, D. Weiss, J. Boelens, P.J. Hanley. Emerging Trends in COVID-19 Treatment: Learning from Inflammatory Conditions Associated with Cellular Therapies. Cytotherapy. 22(9): 474–481, 2020. / Pubmed
     
  26. C.L. Braga, R.P. Silva-Aguiar, D. Battaglini, D.B. Peruchetti, C. Robba, P. Pelosi, P.R.M. Rocco, C.C. Neves, P.L. Silva. The renin-angiotensin-aldosterone system Role in pathogenesis and potential therapeutic target in COVID-19. Pharmacol Res Perspect. 8(4):e00623, 2020. / Pubmed
     
  27. D. Battaglini, P.M.P. Coelho, C. Robba, C. Santos, F.F. Cruz, P. Pelosi, P.R.M. Rocco. Gut Microbiota in Acute Ischemic Stroke: From Pathophysiology to Therapeutic Implications. Frontiers in Neurology. 2020. / Pubmed
     
  28. P.R.M. Rocco, P.L. Silva, C.S. Samary, M.K.H. Syed, J.J. Marini. Elastic power but not driving power is the key promoter of ventilator-induced lung injury in experimental Acute Respiratory Distress Syndrome. Critical Care, 24(1):284, 2020. / Pubmed
     
  29. C. Robba, D. Battaglini, P. Pelosi, P.R.M. Rocco. Multiple Organ Dysfunction in SARS-CoV-2: MODS-CoV-2. Expert Review of Respiratory Medicine. 1-4, 2020. / Pubmed
     
  30. P.R.M. Rocco, J.J. Marini. What have we learned from animal models of Ventilator-Induced Lung Injury? Intensive Care Medicine. 1-4, 2020. / Pubmed
     
  31. V. Martins, A.L. Silva, W.R. Teodoro, A.P.P. Velosa, M.L. Balancin, F.F. Cruz, P.L. Silva, P.R.M. Rocco, V.L. Capelozzi. In situ evidence of collagen V and signaling pathway of found inflammatory zone 1 (FIZZ1) is associated with silicotic granuloma in lung mice. Pathology - Research and Practice. 216(9):153094. 2020. / Pubmed
     
  32. M.C. Barbosa-Silva, P.R.M. Rocco, T. Maron-Gutierrez. The Authors Reply. Critical Care Medicine. 48(7):e634-e635, 2020. / Pubmed
     
  33. D. Battaglini, I. Brunetti, P. Anania, P. Fiaschi, G. Zona, L. Ball, N. Patroniti, A. Schenone, P. Pelosi, P.R.M. Rocco, C. Robba. Neurological manifestations of severe SARS-CoV-2 infection: potential mechanisms and implications of individualized mechanical ventilation settings. Frontiers in Neurology. 11: 845, 2020. / Pubmed
     
  34. S. Horie, B. McNicholas, E. Rezoagli, T. Pham, G. Curley, D. McAuley, C. O'Kane, A. Nichol, C. Santos, P.R.M. Rocco, G. Bellani, J.G. Laffey. Emerging pharmacological therapies for ARDS: COVID-19 and beyond. Intensive Care Med. 11:1-19, 2020. / Pubmed
     
  35. P. Mattos-Silva, N.S. Felix, P.L. Silva, C. Robba, D. Battaglini, P. Pelosi, P.R.M. Rocco, F.F. Cruz. Pros and cons of corticosteroid therapy for COVID-19 patients. Respiratory Physiology & Neurobiology. 280:103492, 2020. / Pubmed
     
  36. N.P. Juffermans, P. Radermacher, J.G. Laffey, J. Villar, M. Schultz, J.L. Diehl, P. Pelosi, C. Karagiannidis, M. Restrepo, G. Perchiazzi, A.A. Raventos, N. Marczin, E. Rezoagli, M. Lipcsey, V. Fanelli, P.R.M. Rocco, E.R. Zanier, M. Takata, J.D. Chiche, G. Ristag, O. Penuelas, L.A. Rodríguez, N.C. Weber, R.C.E. Francis, L. Camporota, L.D.J. Bos, B.V. Patel, M. Pellegrini, M. Wepler, K. Wakabayashi, J.B.M. van Woensel, A. Zanella, J.A.L. Balanza, L.M.A. Heunks, P. Pickkers, R.A. Bem, J.A. Graw. The importance of discovery science in the development of therapies for the critically ill. Intensive Care Medicine Experimental. 8:17, 2020. / Pubmed
     
  37. C. Robba, D. Battaglini, P. Pelosi, P.R.M. Rocco. Response to letter to the editor: Catastrophic antiphospholipid antibody syndrome and multiple organ dysfunctions in critically ill patients with COVID-19. 2020. / Pubmed
     
  38. J. Wittenstein, M. Scharffenberg, A. Braune, R. Huhle, T. Bluth, M. Herzog, A. Güldner, L. Ball, F. Simonassi, I. Zeidler-Rentzsch, M.F. Vidal Melo, T. Koch, P.R.M. Rocco, P. Pelosi, J. Kotzerke, M.G. de Abreu, T. Kiss. Effects of variable versus nonvariable controlled mechanical ventilation: response to comment. British Journal Of Anaesthesia. 124: 430-9, 2020. / Pubmed
     
  39. L.H.A. Silva, M.C. Silva, J.B. Vieira, E.C.D. Lima, R.C. Silva, D.J. Weiss, M.M. Morales, F.F. Cruz, P.R.M. Rocco. Magnetic targeting increases mesenchymal stromal cell retention in lungs and enhances beneficial effects on pulmonary damage in experimental silicosis. Stem Cells Transl Med. 9(10):1244-1256, 2020. / Pubmed
     
  40. C. Robba, D. Battaglini, P. Pelosi, P.R.M. Rocco. Response to letter to the editor: Catastrophic antiphospholipid antibody syndrome and multiple organ dysfunctions in critically ill patients with COVID-19. Expert Rev Respir Med. 1-2. 2020. / Pubmed
     
  41. M.N. Lima, H.A. Oliveira, P.M. Fagundes, V. Estato, A.Y.O. Silva, R.J.R.X. Freitas, B.A.R. Passos, K.S. Oliveira, C.N. Batista, A.L. Vallochi, P.R.M. Rocco, H.C. Castro-Faria-Neto, T. Maron-Gutierrez. Mesenchymal stromal cells protect against vascular damage and depression-like behavior in mice surviving cerebral malaria. Stem Cell Research & Therapy. 11(1):367. 2020. / Pubmed
     
  42. R.S. Mendes, G. Martins, M.V. Oliveira, N.N. Rocha, F.F. Cruz, M.A. Antunes, S.C. Abreu, A.L. Silva, C. Takiya, P.M. Pimentel-Coelho, C. Robba, R. Mendez-Otero, P. Pelosi, P.R.M. Rocco, P.L. Silva. Iso-Oncotic Albumin Mitigates Brain and Kidney Injury in Experimental Focal Ischemic Stroke. Frontiers in Neurology. 11:1001, 2020 / Pubmed
     
  43. N.G. Blanco, M.A. Antunes, N. Machado, L.L. Castro, C. Takiya, P.L. Silva, F.F. Cruz, J.D. Silva, P.R.M. Rocco. Therapeutic effects of extracellular vesicles obtained from bone marrow-derived, adipose tissue-derived, and lung-derived mesenchymal stromal cells on the lung and distal organs in experimental sepsis. Cytotherapy. 22 (5), S24, 2020.
     
  44. F.F. Cruz, L.P. de Carvalho, L.L. Castro, S.C. Abreu, J.B. Vieira, R. Trabach, L.A. Gonçalves, P.L. Silva, P.R.M. Rocco. Protective therapy with mitochondria isolated from mesenchymal stromal cells in a sepsis model. Cytotherapy. 22 (5), S78-S79, 2020.
     
  45. S.R. Enes, D. McKenna, C. Santos, K.D. Liu, P.R.M. Rocco, M. Matthay, D.J. Weiss. Inflammatory microenvironment in ARDS patients polarize clinically utilized MSCs towards a pro-inflammatory MSC phenotype. Cytotherapy. 22 (5), S99, 2020.
     
  46. R.P. Silva-Aguiar, D.B. Peruchetti, P.R.M. Rocco, A.H Schmaier, P.M.R. Silva, M.A. Martins, V.F. Carvalho, A.A.S. Pinheiro, C.C. Neves. Role of the renin angiotensin system in the development of severe COVID-19 in hypertensive patients. American Journal of Physiology - Lung Cellular and Molecular Physiology. 319(4):L596-L602, 2020. / Pubmed
     
  47. D. Battaglini, C. Robba, S. Caiffa, L. Ball, I. Brunetti, M. Loconte, D.R. Giacobbe, A. Vena, N. Patroniti, M. Bassetti, A. Torres, P.R.M. Rocco, P. Pelosi. Chest physiotherapy: an important adjuvant in critically ill mechanically ventilated patients with COVID-19. Respiratory Physiology & Neurobiology. 282:103529. 2020. / Pubmed
     
  48. E.Y. Suzuki, A. Simona, A.L. Silva, M.I. Amaro, G.S. Almeida, L.C. Agra, L.M. Cabral, P.R.M. Rocco, A.M. Healy, V.P. Sousa. Effects of a novel roflumilast and formoterol fumarate dry powder inhaler formulation in experimental allergic asthma. International Journal of Pharmaceutics. 588:119771. 2020. / Pubmed
     
  49. T. Maron-Gutierrez, P.R.M. Rocco. Cell-free therapies: novel approaches for COVID-19. Frontiers in Immunology. 11:583017, 2020. / Pubmed
     
  50. T.D. Ramos, J.D. Silva, A.M. Fonseca-Martins, J.E.S. Pratti, L. Firmino-Cruz, D. Maciel-Oliveira, J.S. Santos, J.I.N. Tenorio, A.F. Araujo, C.G. Freire-de-Lima, B.L. Diaz, F.F. Cruz, P.R.M. Rocco, H.L.M. Guedes. Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis. Stem Cell Research & Therapy. 11(1):374, 2020. / Pubmed
     
  51. C.L. Braga, N.S. Felix, D.E. Teixeira, J.B. Vieira, R.P. Silva-Aguiar, R.M. Bose, M.A. Antunes, N.N. Rocha, C. Caruso-Neves, F.F. Cruz, P.R.M. Rocco, P.L. Silva. Niclosamide attenuates lung vascular remodeling in experimental pulmonary arterial hypertension. Eur J Pharmacol. 887:173438. 2020. / Pubmed
     
  52. G.C. Rodrigues, N.N. Rocha, L.A. Maia, I. Melo, A.C. Simões, M.A. Antunes, F.F. Bloise, J. Woyames, W.S. Silva, V.L. Capelozzi, G. Abela, L. Ball, P. Pelosi, P.R.M. Rocco, P.L. Silva. Impact of experimental obesity on diaphragm structure, function, and bioenergetics. Journal of Applied Physiology. 129(5):1062-1074, 2020. / Pubmed
     
  53. D. Battaglini, D.S. Gieroba, I. Brunetti, N. Patroniti, G. Bonatti, P.R.M. Rocco, P. Pelosi, C. Robba. Mechanical ventilation in neurocritical caresetting: a clinical approach. Best Practice & Research. 2020.
     
  54. D. Battaglini, G. Santori, K. Chandraptham, F. Iannuzzi, M. Bastianello, F.Tarantino, L. Ball, D.R. Giacobbe, A. Vena, M. Bassetti, M. Inglese, A. Uccelli, P.R.M. Rocco, N. Patroniti, I. Brunetti, P. Pelosi, C. Robba. Neurological complications and noninvasive multimodal neuromonitoring in critically ill COVID-19 patients. Frontiers in Neurology. 11:602114, 2020. / Pubmed
     
  55. D. Battaglini, P. Anania, P.R.M. Rocco, A. Prior, G. Zona, P. Pelosi, P. Fiaschi. Escalate and de-escalate therapies for intracranial pressure control in traumatic brain injury. Frontiers in Neurology. 11:564751, 2020. / Pubmed
     
  56. M. Khoury, P.R.M. Rocco, D.G. Phinney, M. Krampera, I. Martin, S. Viswanathan, J.A. Nolta, K. LeBlanc, J. Galipeau, D.J. Weiss. Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential. Cytotherapy. 22(11):602-605. 2020. / Pubmed
     
  57. S.C. Abreu, T.H. Hampton, E. Hoffman, J. Dearborn, A. Ashare, K. Sidhu, D. Matthews, A. Krasnodembskaya, K. English, B. Mahon, C. Santos, F.F. Cruz, D. Chambers, K Liu, M. Matthay, R. Cramer, B. Stanton, P.R.M. Rocco, M. Wargo, D J Weiss, S.R. Enes. Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells. Am. J. Physiol Lung Cell Mol Physiol. 319(6): L908-L925, 2020. / Pubmed
     
  58. C. Robba, D. Battaglini, C.S. Samary, P.L. Silva, L. Ball, P.R.M. Rocco, P. Pelosi. Ischaemic stroke-induced distal organ damage: pathophysiology and new therapeutic strategies. Intensive Care Med Exp. 8 (Suppl 1): 23, 2020. / Pubmed
     
  59. L. Ball, A. Serpa-Neto, V. Trifiletti, M. Mandelli, I. Firpo, C. Robba, M.G. Abreu, M.J. Schultz, N. Patroniti, P.R.M. Rocco, P. Pelosi. Effects of higher PEEP and recruitment manoeuvres on mortality in patients with ARDS: a systematic review, meta-analysis, meta-regression and trial sequential analysis of randomized controlled trials. Intensive Care Med Exp. 8 (Suppl 1): 39, 2020. / Pubmed
     
  60. R.S. Mendes, P. Pelosi, M.J. Schultz, P.R.M. Rocco, P.L. Silva. Fluids in ARDS: more pros than cons. Intensive Care Med Exp. 8 (Suppl 1): 32, 2020. / Pubmed
     
  61. C. Robba, D. Siwicka-Gieroba, A. Sikter, D. Battaglini, W. Dabrowski, M.J. Schultz, E. Jonge, C. Grim, P.R.M. Rocco, P. Pelosi. Pathophysiology and clinical consequences of arterial blood gases and pH after cardiac arrest. Intensive Care Med Exp. 8 (Suppl 1): 19, 2020. / Pubmed